2 Single beds
Deluxe Twin with shared bathroom
121 ft²
This twin room has a satellite TV and a microwave.










Highlights, description and the facilities guests use most.
A budget-friendly base in San Francisco’s downtown core.
Desmond Hotel San Francisco offers a straightforward stay for travelers seeking a central location at an affordable rate. This no-frills property emphasizes practicality, with basic guest rooms, 24-hour front desk service, and Wi-Fi in public areas. Its historic building, modest yet functional, reflects the downtown character of San Francisco, making it a convenient base for visitors attending conventions, exploring the city’s attractions, or seeking proximity to transit.
Stay in San Francisco - Rooms for Every Budget
In every room: Flat-screen TV · Refrigerator · Fan · Microwave
Location, travel times, listing details and guest feedback
Desmond Hotel is at 42 6th St in San Francisco. San Francisco International Airport takes around a quarter of an hour by car without traffic. Powell Street subway station is a short walk away; Warfield Theatre is a couple of minutes on foot, and Yerba Buena Gardens is a short walk away.
Explore the best attractions, shopping destinations, and important places near Desmond Hotel.
31 amenities in 11 categories.
Check-in, check-out and house rules.
Explore San Francisco
Situated on 6th Street, the hotel sits between Market Street and Mission Street, placing guests within walking distance of the Powell Street BART station. Surrounding blocks feature coffee shops, casual dining, and quick access to shopping centers.
Union Square – A lively plaza surrounded by department stores and restaurants.
Moscone Center – Major convention hub, hosting international events.
Westfield San Francisco Centre – Indoor mall with fashion and food options.
San Francisco Museum of Modern Art (SFMOMA) – Renowned contemporary art collection.
Powell Street Cable Car Line – A classic way to see the city.
The area is urban and busy, with a mix of visitors and locals. Guests can expect lively streets during the day and easy access to downtown attractions, though the neighborhood has a gritty edge common to central San Francisco.
Check rates for Desmond Hotel San Francisco and secure your downtown stay.
Loved by Guests, Trusted for Excellence
I don’t know where to begin there’s homeless people outside the front entrance all day, the room is maybe 12by12 has no toilet but has a sink that has brown water come out each time you use it. you can’t adjust the temperature in the room there’s stains all over the comforter. It’s really just a run down motel in a bad area
Liked: The hotel is terrifying, I couldnâ≢t stay there for 5 minutes The elevator door was broke, a lot of homeless on street, they scare. DONâ≢T GO THERE Disliked: Everything
Liked: Only location Disliked: Cleanliness very poor. They never mentioned the sheets. the hotel smells so crappy
Liked: That they had HBO Disliked: The location is sketchy and they require a large cash deposit
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Located near Desmond Hotel, you'll find an array of delightful dining and coffee spots to suit every taste. Whether you're in the mood for a quick snack or a leisurely meal, the nearby establishments provide a convenient and enjoyable dining experience during your stay in San Francisco.